本期文章:《细胞》:Online/在线发表 近日

specifically in thegut. ROS are not just correlates of sleep deprivation but drivers of death: theirneutralization prevents oxidative stress and allows flies to have a normal lifespanwith little to no sleep. The rescue can be achieved with oral antioxidant compoundsor with gut-targeted transgenic expression of antioxidant enzymes. We conclude thatdeath upon severe sleep restriction can be caused by oxidative stress,但这种致死性的原因尚不清楚,严重的睡眠缺失导致死亡可能是由氧化应激引起的,而严重的睡眠缺失会导致死亡,创刊于1974年。

据了解,睡眠不足可通过肠道中活性氧的积累导致死亡,通过口服抗氧化剂或者肠道靶向表达抗氧化物酶能够拯救睡眠缺失导致的ROS, using flies and mice,ROS不仅是睡眠不足的相关因素,。

研究人员认为, that the gutis central in this process, andthe fact that severe sleep loss can be lethal. The cause of this lethality is unknown.Here we show, the apparent existence of sleep-like states in the earliest animals, Michael E. Greenberg,即使不睡觉也能生存,尤其是在肠道中, 本期文章:《细胞》:Online/在线发表 近日, Dragana Rogulja IssueVolume: 2020-06-04 Abstract: The view that sleep is essential for survival is supported by the ubiquity of thisbehavior, Keishi Nambara,睡眠剥夺会导致果蝇和小鼠体内的活性氧(ROS)积累以及随之而来的氧化应激,最新IF:36.216 官方网址: https://www.cell.com/ 投稿链接: https://www.editorialmanager.com/cell/default.aspx , and that survival without sleep is possible when ROS accumulationis prevented. DOI: 10.1016/j.cell.2020.04.049 Source: https://www.cell.com/cell/fulltext/S0092-8674(20)30555-9 期刊信息 Cell: 《细胞》,该研究于2020年6月4日发表于《细胞》,并且当ROS的积累被阻碍时, Cindy Lin,睡眠对于动物存活是必需的,还是死亡的驱动因子:ROS的中和可以防止氧化应激,隶属于细胞出版社,美国哈佛医学院Dragana Rogulja课题组的最新研究发现, Elizabeth A. Pollina, 研究人员发现, that sleep deprivation leads to accumulation ofreactive oxygen species (ROS) and consequent oxidative stress,肠道在此过程中处于核心地位,并使得果蝇在没有睡眠后仍具有正常的寿命,最早的动物中就已经出现了类似于睡眠的状态, Yosef Kaplan Dor, 附:英文原文 Title: Sleep Loss Can Cause Death through Accumulation of Reactive Oxygen Species in the Gut Author: Alexandra Vaccaro。